Thursday, July 22, 2010

Cellular Philosophy

Vaidurya Pratap Sahi: Cells too are designated for their Karmas...!!!
17 January at 06:07

Rammohan Shukla: They form the RAMRAJYA the so called utopian world!
18 January at 08:35

Vaidurya Pratap Sahi: Very true but, In many places , humans are subjected to work based on their birth. But this is against nature. The basic units of life- the cell- has a choice to develop into a tissue which it wants. They form their own niches. Unless societies across the globe start working on the principle followed by cells, ramrajya will be a dream
18 January at 10:59 ·

Rammohan Shukla: Once they are in there niche They can't (very less probability what you say?) change there type. The development happens under strict bylaws (replication fidility). To change them you have to change there (the templates to undergo replication fidility)
No good change can create tumor :)!
Integrity (karma) is a change IN but not change OF! ( Your comments please)
18 January at 11:16

Rammohan Shukla: Integrity (Dharma)
18 January at 11:22

Subramanian Sankranarayanan: actualy each cell is a perfect yogi !!! and once it gets selfish it does not last longer,it takes the entire system away...
18 January at 12:09

Rammohan Shukla: I guess its other way round Sir. each cell is selfish and self organized. If it shows any altruistic behaviour it will be a disaster. Interaction with others are there prescribed duties. The best thing about them is that they know there constitutional position and duties which we human often forget.
Selfishness is a virtue. Altruism is a refuge for selfless
19 January at 08:37

Rajiv Krishna Parvathaneni : i agree....cell has the ability to be whatever it wants but it does the greater good of being whats essential
19 January at 09:45

Vaidurya Pratap Sahi: I give 10 on 10 to ram bhaiya and rajiv
19 January at 09:55

Rammohan Shukla : Not yet over Kaju, we have to think over few more issues
what is the role of genome (the inherited iformation) does that define the dharma (Remember, There is change in but not the change of) of the cell (before its birth) or tradition of the cell (what is tradition ? The templates of replication!). what is the role of membrane which limits the expansion of the cell (Is it analogous to the social and ethological membranes).
19 January at 10:31

Rajiv Krishna Parvathaneni: epigenetics and apoptosis are 2 things which i feel signify dharma and karma...but then again how do cells recognise the cycle of life and death...self perpetuity is deeply igrained in us....even when a plant recognises danger to itself and knows it would not survive...it does the next possible thing....reproduce....where is the concept of moksha in nature???
19 January at 11:01

Vaidurya Pratap Sahi: Rajiv, i think that the genome signifies the dharma(as pointed by ram bhaiya) and epigenetics, apoptosis etc are the karmas. from my point of view, the genome is dharma because in all the cells of an individual the genome remains the same (in a society dharma remains the same);
as in real life, we are defined by our karmas, the karmas of the cell (epigenetics etc ...) leads to its end. By end i dont just mean death, end includes its final place. example it may end up being a neuron, or a cell of epethelial tissue, or it may die or it may become cancerous...etc etc...
19 January at 15:31

Vaidurya Pratap Sahi: Ram bhaiya, i agree with our view point that the Genome may be the dharma. And yes, all these replications, translation, transcription, etc are traditions which the cell follows to maintain its identity. the cells know that they need not loose their identity for the greater cause (the cause of life of the individual). i feel these cellular traditions make the cells ready for their future course of life(their karmas) and on a broader perspective we can say that they help cells to maintain dharma(the genome).
As for your question on the role of membranes: i think it is like the social and ethological membranes, but here (in case of cells) it is necessary; but in social and ethological context i dont think it is always necessary to have membranes.
please comment on Rajivs question where is the concept of moksha in nature???"
19 January at 15:50

Rammohan Shukla : I guess we are going away from the topic. The cell can be compared to society (organization,system) not individual. we have to define the an ideal society not an individual. moksha can be in realization. and realization of moksha is for individual not for the society.
Kaju, search where is Hirarchy in cell?
genome can have many function
including Traditions, History, and common factor of all the cellular component (The identity!)
20 January at 14:22

Rammohan Shukla: There are logical redundancies in nature naovality is created by various modes of regulation of similar logics so the cell may not be an exactly anlogous to society try focusing on types and way of regulation.
20 January at 14:26

Rammohan Shukla :Why you guys have stopped discussing?
Rajeev I guess at organizational level we can compare Apoptosis as an ethical move....
Where Ethics are just like balancing the reaction you add or delete from either side to make it stable!
In one of the "jeff's views” It was mentioned that stepping back is also leadership. Please read it if you find time.
22 January at 09:24

Vaidurya Pratap Sahi: Please define ethics and then I will comment...
22 January at 15:26

Rammohan Shukla: They are the bylaws to judge w/er the action taken is right or wrong. It is something which helps the organization/system to remain in a state of
stability.
we have ethics probably To avoid chaos and bring order. Apoptosis is an
ethical move to bring order. This is the process where in the cell can be considered individual as It undergoes apoptosis to propagate the higher
WHOLE (the body) of which it is a part.
Just think on these questions now.....
Does cell has a goal? Does Society has a goal? If so so what is it?
22 January at 16:25 via Email reply

Vaidurya Pratap Sahi: There is hierarchy amongst cells which depends on the type of tissue it belongs to. And mostly this hierarchy is achieved through time of cell cycle. I will deal with this in detail later. Before that I want to answer your question related to cell and society.
24 January at 22:27

Vaidurya Pratap Sahi: The goals of society have changed time and again. Goals depend mostly on the needs/demands (for example food, defence, propogation, etc) and sometimes even on the desires (expansion of kingdoms, promotion of particular religion, etc) of a particular society. Similarly , cells' goals depend on needs/ requirements of the body. Example, if need be , a cell may differentiate or at same time undergo harakiri ( apoptosis). These goals (both of cell and society) are not dependant on an individual but on the interaction of individuals .
24 January at 22:43

Vaidurya Pratap Sahi: Please upload your comments here...
26 January at 11:02

Rammohan Shukla: The only goal is to SUSTAIN! Sustain the order!
The Society has to sustain Values, tradition, culture.....
Homeostasis "The change in but not change of" is how the cell sustains it self!
traditions are some thing which needs to be passed on from one generation to another. They are like DNA template.
Just observe the unicellular prokaryotes and viruses don't bother to pass on the template as it is to the next generation, they don't have proof reading of the replicated template. but what makes the multicellular organism to cross check its replication several time before passing on the template to the next generation. Is it that it knows that daughter cell is going to be in a society.
Many things to write.....!
26 January at 11:03

Vaidurya Pratap Sahi: your observation is worth appreciation. but i have a doubt.
At times we need mutations for our survival or keep the species. if there is this maintenance of genome all the time how will the organism evolve.... what about the importance of mutations in biology?
27 January at 13:50

Rammohan Shukla: ‎"Change in but not the change of" is key to all your questions kaju. most of
the time we confuse adaptations as evolution. Adaptations are conservative. evolution targets behaviours only!
I strongly believe that mutations are not random it is a programmed
adaptation.
your comments please
27 January at 13:58

Vaidurya Pratap Sahi: ‎"Change in but not the change of"
can you explain this elaborately. i am unable to comprehend it completely.
can you, also, validate your view that "mutations are not random it is a programmed"
27 January at 14:08

Rammohan Shukla :give me some time
27 January at 14:32

Vaidurya Pratap Sahi Cells are sleeping
04 March at 14:25

Rammohan Shukla: you made them sleep
04 March at 14:27

Rammohan Shukla: Our Society " Out with the Old, In with the new"
Cell as Society "On with the Old, In with the new"
What are the difference between societies of a developed nation, developing nation and those of underdeveloped nations?
05 March at 09:28

Vaidurya Pratap Sahi: The banyan tree, which has seen the world for quite a few hundred years, believes that the very existence of mankind would have been in question had humans not learnt to "Out with the Old, In with the new"
this is something which is imprinted in the very human nature. had it not been for this, the humans would not have had civilized. fortunately or unfortunately this is directly proportional to the development of any nation/ society. the more the people follow this , more is the development (look around and see all the developed nations) This brings us back to the crossroads where we have to decide whether we need to follow what has been going on or create a new path/ trend...
05 March at 12:57

Rammohan Shukla: And what does the "time line" says about this?
05 March at 13:27

Vaidurya Pratap Sahi : the timeline agreed to the banyan but it had a tone of meloncholy and doubt. The banyan which was much younger to the timeline asked him "thou are the history, the present and will be the future... tell me o great one what is the cause of this melancholy?" To this the timeline replied " O young one. oh ho ho ho (coughs) Human civilisation , which once i thought was the best thing which was connected to me, is the cause of my melancholy. the humans have not been discreet in their ways of civilisation. I agree to the concept of "Out with the Old, In with the new" but with a little bit of discretion... i agree that there is a need for innovation but not at the cause of bringing harm to the Earth. i have seen in the past couple of centuries changes happening which have brought me to this crossroad"
The conversation went on and in it came the topic of genome to which the timeline said "as per the saying Out with the Old, In with the new, the very epitome of a being - the genome- , also follows this on a long term basis; and this is why there is so much diversity on this planet. But the genome gives time to its new forms to adjust with the environment. similar to the genome if the humans become discreet in their march for development, i will have a longer life...." with these words the timeline went in trance.......
05 March at 13:44

Rammohan Shukla :The Banyan Tree: O great one, I belong to this earth and earthly things have
no permanence. as like others I shed my leaves which are old and wear new in every season. but my new generations which come out of me and stay with me
keeps me in there core and the every subsequent generation follows this tradition of "In with the Old and In with the new". I have a long life span
and I witness many generations of change, those helping me to sustain
through changes are no one but my new generations who have "Value" of my presence. Now I realize that its not me in the core of my young generations
but the Values.
In evolution also we witness many phenomenon of "In with the Old and In with
the new" The best example is the human Brain it self. In fact the primates
have the best evolved neocortex which is new in the periphery and old in the core just like me "the banyan"
10 March at 10:49