Monday, November 22, 2010

Makorin and The Trinity

Makorin is a marker for stem cells: Brahma (Creator)
Makorin plays a role in embryogenesis and early development: Vishnu (Preserver)
Makorin acts as E3 Ligase during ubiquitination: Shiva (destroyer)


Reference

1.Gray, T. A., A. H. Hernandez, L. H. Carey, M. A. Schaldach, M. J. Smithwick, K. Rus, J. A. M. Graves, C. L. Stewart and R. D. Nicholls. 2000. Genomics 66:76–86.

2.Lee E.W, M.S. Lee, S. Camus, J. Ghim, M. Yang, W. Oh, N. Ha, D. P. Lane and J. Song. 2009. The EMBO Journal. 28: 2100–2113.

3.http://www.wipo.int/pctdb/en/wo.jsp?WO=2008055361&IA=CA2007002034&DISPLAY=STATUS
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2 comments:

  1. HarryNovember 23, 2010 at 12:03 AM

    Apocalypse !!!

    ReplyDelete
  2. AnonymousDecember 5, 2010 at 7:40 PM

    Its important in science to distinguish between concepts and mechanisms.concepts are substrate independent, whereas mechanisms always depend on some kind of substrate. concepts borrowed from other disciplines can assist in addressing a problem or gaining new insight understanding mechanisms always require experiments on the relevent substrate.
    REDUCTIONISM IS GOOD FOR INSIGHT BUT THE WHOLE DEMANDS ITS EXPLANATION THROUGH ITS OWN ELEMENTS.

    ReplyDelete

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